What is Gastroparesis & Why Does it Occur?
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What is Gastroparesis & Why Does it Occur?

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What is Gastroparesis & Why Does it Occur?

Gastroparesis is a condition that affects the muscles in the stomach, removing its ability to empty food into the small intestine like usual. This digestive condition can lead to multiple uncomfortable and even debilitating symptoms. There are numerous potential causes of gastroparesis, with several factors contributing to the condition’s development. One known cause of gastroparesis that has gained publicity in recent months is the diabetes-treatment drug Ozempic. In this article, we explore what gastroparesis is, how it can be caused, and what treatment options are available for this condition.

Understanding Gastroparesis

Common symptoms of gastroparesis include bloating, abdominal pain, vomiting, nausea, and feeling full after eating small amounts of food. To accurately diagnose whether a patient has gastroparesis, a series of tests are carried out. Some of the tests carried out may include:

  • A breath test to check for bacterial overgrowth
  • A Gastric emptying study to see how fast food leaves the patient’s stomach
  • Upper GI endoscopy to examine the inside of the esophagus and stomach

Multiple types of gastroparesis can be diagnosed. If no underlying cause for the condition can be determined, a patient is diagnosed with idiopathic gastroparesis. Postsurgical gastroparesis occurs after certain abdominal surgeries. Diabetic gastroparesis develops in people with diabetes. Any type of gastroparesis can vary significantly in severity, with patients experiencing effects ranging from mild to life-changing. 

Primary Causes of Gastroparesis

Gastroparesis can be caused by any combination of multiple factors, including the following:

  • Diabetes: Chronically high blood sugar levels can damage the vagus nerve, which controls the muscles in the stomach and intestines. Damage to this nerve can result in delayed stomach emptying. 
  • Surgical Procedures: Certain surgeries, particularly those involving the stomach or esophagus, can damage nerves or muscles responsible for stomach emptying. This can cause postsurgical gastroparesis. 
  • Medications: Some medications slow the digestive process, thus contributing to gastroparesis. Certain antidepressants and narcotic pain relievers are examples of drugs capable of having this effect. 
  • Other Medical Conditions: Autoimmune diseases like scleroderma, neurological disorders like Parkinson’s disease, and viral infections can cause gastroparesis or worsen a patient’s symptoms.

Secondary and Lesser-Known Causes

  • Idiopathic Gastroparesis: In roughly 30% of cases, the cause of gastroparesis remains unknown. These cases are referred to as idiopathic gastroparesis.
  • Nutritional Deficiencies: Deficiencies in certain vitamins and minerals have been linked to impaired stomach motility. While this may not be the primary cause of a person’s gastroparesis, this may factor into the severity of their condition. 
  • Lifestyle Factors: Chronic stress, a sedentary lifestyle, and a poor diet high in fiber and fat can worsen the symptoms of gastroparesis.
  • Ozempic: The relatively new diabetes medication Ozempic has caused some worrisome side effects in users, including gastroparesis. Although research on this medication’s effects is ongoing, patients taking this medication should be aware of this potential treatment risk. 

Managing and Treating Gastroparesis

As of right now, there is no cure for gastroparesis. However, some treatments can help patients manage their symptoms and enjoy a higher quality of life. Dietary adjustments are a key component of most treatments. Patients may be encouraged to eat more frequent, smaller meals and avoid high-fiber or fatty foods that are challenging to digest. 

Medications can also alleviate some of the worst symptoms of gastroparesis. Prokinetic drugs can stimulate stomach muscle contractions and antiemetics can control vomiting and nausea. In severe cases, options like feeding tubes or gastric electrical stimulation (to improve stomach emptying) may be considered. While not a cure-all, lifestyle modifications such as stress management techniques and regular exercise can also be useful. 

Recognizing & Addressing the Challenges of Gastroparesis

Gastroparesis can be a challenging condition to deal with, but by developing a deeper understanding of the condition and its causes you can manage it effectively. If you experience persistent symptoms that suggest gastroparesis, contact a doctor as soon as possible to receive a proper diagnosis. With the right approach, it is possible to manage this health condition and live a fulfilling life. We hope this article helps you or your loved one overcome the effects of gastroparesis and live a healthy, happy life!